| Glucose Transport and Metabolism in Chondrocytes
- a Key to Understanding Chondrogenesis, Skeletal Development and
Cartilage Degradation in Osteoarthritis
| Article
Summary: |
There
are many mechanisms which affect the continued degradation
associated with arthritis. Glucose and its derivatives
are important in the building of cartilage and repairing
damage. Chondrocytes utilize the glucosamine sulfate
to build the extra cellular matrix, or the bone
and joint tissues. One possible explanation for
arthritis may be a disorder of the usage of glucose
and therefore a failure to fully create and repair
cartilage. The use of glucosamine then is one supplement
that may help to correct the metabolic disorder
and lead to the repair of the degradation and the
alleviation of pain. |
|
Authors:
Mobasheri A. Vannucci SJ. Bondy CA. Carter SD. Innes JF. Arteaga
MF. Trujillo E. Ferraz I. Shakibaei M. Martin-Vasallo P.
Institution:
Connective Tissue Research Group, Musculoskeletal Physiology Laboratory,
Faculty of Veterinary Science, University of Liverpool, Liverpool,
United Kingdom. a.mobasheri@liverpool.ac.uk
Country of Publication:
Spain
Source:
Histology & Histopathology. 17(4):1239-67, 2002 Oct.
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