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Glucosamine Sulfate Use and Delay of Progression
of Knee Osteoarthritis - a 3-year, Randomized, Placebo-controlled,
Double-blind Study.
| Article
Summary: |
A
drawback of many medicines to treat arthritis is
that none of them are able to slow down or stop
the progressive degeneration of the joints affected
by arthritis. This study looked at the effect of
glucosamine sulfate on the progression of arthritis
over a 3 year period. Participants were separated
into two groups, one to receive 1500 mg a day of
glucosamine sulfate, the other to receive a placebo
daily. The Lesquesne index and the WOMAC were administered
to monitor pain feelings, and the joint space of
the site of arthritis was monitored for progression.
The joint space narrowing continued with the use
of the placebo, but was stopped with the use of
the glucosamine sulfate. The glucosamine sulfate
also produced a greater alleviation of pain. As
a long term treatment, glucosamine sulfate was effective
at reducing pain of osteoarthritis and stopping
the joint space narrowing. There were no side effects
reported. |
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Authors:
Pavelka K. Gatterova J. Olejarova M. Machacek S. Giacovelli G. Rovati
LC.
Institution:
Department of Medicine and Rheumatology, Charles University, Prague,
Czech Republic. pavelka@revma.cz
Country of Publication:
United States
Source
Archives of Internal Medicine. 162(18):2113-23, 2002 Oct 14.
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