| Glucosamine Research
Thank you for visiting the Glucosamine Research Center. Here you
will be able to find current research on glucosamine, usage information,
clinical abstracts, lay person interpretations, and even a search
feature to effortless find the information you need. Below you will
find links to actual cited peer reviewed clinical studies and an
easy to understand interpretation of every one of the results.
Evaluation
of Glucosamine Sulfate Compared to Ibuprofen for the Treatment of
Temporomandibular Joint Osteoarthritis
Glucosamine was compared to Ibuprofen, and common over the counter
Ibuprofen had a 300% drop out rate as compared to Glucosamine with
respect to stomach upset. Patients taking Glucosamine experienced
a greater decrease of TMJ pain, greater function and less effects
of pain as compared to Ibuprofen.
Glucosamine
Sulfate: A Study
Successful treatment of osteoarthritis must control pain and should
slow down or reverse the progression of osteoarthritis. Biochemical
and pharmacological data as well as animal and human studies has
demonstrated that Glucosamine is able to slow down or reverse the
effects of osteoarthritis as well as control the associated pain.
Glucosamine
Sulphate In Osteoarthritis - A Systematic Review
This was a study that reviewed other studies that have taken place
on Glucosamine, Ibuprofen (a NSAID) and placebo. In every study,
Glucosamine was shown to be always be more effective than placebo
and be atleast as effective (if not more so) than Ibuprofen, which
carries risks when it is used for long periods of time. Overall,
Glucosamine has been shown to be an effective therapeutic nutraceutical
for certain kinds and locations of arthritis with almost no side
effects.
Glucosamine
Therapy for Treating Osteoarthritis
This is another follow up study that surveyed the existing body
of studies out there and provided a summary of the findings. The
conclusion suggests that Glucosamine is consistently more effective
than placebo and at least as effective if not more so than NSAIDs
such as aspirin or ibuprofen, without the long term eroditive effects
on some of the body's major organs that are typical of many NSAIDs.
Glucose
Transport and Metabolism in Chondrocytes
This study studied the effect of Glucosamine and Vitamin C on the
"development, maintenance, repair, and remodeling of cartilage.
Recent studies suggest that degeneration of cartilage may be triggered
by metabolic disorders of glucose balance." This study poses
the point that Glucosamine and other glucose derived vitamins such
as Vitamin C would be helpful in treating degenerative joint disorders.
Efficacy
and Safety of Intramuscular Glucosamine Sulfate in Osteoarthritis
of the Knee
This study found that Glucosamine is at least as effective as NSAIDs,
without all of the harmful effects of long term NSAID therapy and
certainly much more effective than placebo.
Anti-arthritic
Effects of Glucosamine Sulfate Studied in Animal Models
Glucosamine sulfate was found to be effective at reducing the inflammation
in the joints of the rats. Glucosamine sulfate is considered to
be a much safer form of treatment for arthritis.
Pharmacokinetics
of Glucosamine in the Dog and in Man
Oral (e.g. Liquid) Glucosamine was shown to be absorbed in dog models
at an effectively same rate as IV administration. (Can you imagine
trying to give your dog a daily shot?) It also shows that much of
the Glucosamine stays in the body (rebuilding cartilage and easing
pain) for a few days after administration, so that three daily doses
should about as effective as one daily dose.
The
Role of Glucosamine Sulfate and Chondroitin Sulfates in the Treatment
of Degenerative Joint Disease
In treating arthritis, the most effective treatment would provide
aid in relieving pain as well as providing some repair for the degradation
of the joints involved. Various studies support the use of glucosamine
sulfate in its ability to both relieve pain and provide some repair
for the joint.
Glucosamine
Sulphate - A Controlled Clinical Investigation In Arthrosis
A follow up study (published in 1981!) was conducted to further
test the effectiveness of glucosamine treatment in primary or secondary
osteoarthritis and the same results were reported. No glucosamine
related side effects were encountered.
More
Clinical References for Glucosamine and Chondroitin Safety and Side
Effects
Be sure to visit the Glucosamine
Product Guide for a review of commercially available glucosamine
products broken down by 9 different categories such as price per month, quality and type. Learn what the best products out there are
and how we ranked each. |
