Glucosamine Research (page 3)
Evaluation of Glucosamine Compared to Ibuprofen for the Treatment of Temporomandibular Joint Osteoarthritis
Glucosamine was compared to Ibuprofen. Ibuprofen had a 300% drop out rate as compared to glucosamine with respect to stomach upset. Patients taking glucosamine experienced a greater decrease in TMJ pain, greater range-of-motion and far fewer side effects.
Glucosamine: A Study
Successful treatment of osteoarthritis must control pain and should slow down or reverse the progression of osteoarthritis. Biochemical and pharmacological data as well as animal and human studies has demonstrated that glucosamine is able to slow down or reverse the effects of osteoarthritis as well as control the associated pain.
Glucose Transport and Metabolism in Chondrocytes
This study studied the effect of glucosamine and Vitamin C on the development, maintenance, repair, and remodeling of cartilage. Recent studies suggest that degeneration of cartilage may be triggered by metabolic disorders of glucose balance. This study poses the point that glucosamine and other glucose derived vitamins such as Vitamin C would be helpful in treating degenerative joint disorders.
Efficacy and Safety of Intramuscular Glucosamine in Osteoarthritis of the Knee
This study found that glucosamine is at least as effective as NSAIDs, without all of the harmful effects of long term NSAID therapy and certainly much more effective than placebo.
Anti-arthritic Effects of Glucosamine Studied in Animal Models
Glucosamine was found to be effective at reducing the inflammation in the joints of rats. Glucosamine is considered to be a much safer form of treatment for arthritis.
Pharmacokinetics of Glucosamine in Dog and Man
Oral (e.g. Liquid) glucosamine was shown to be absorbed in dog models at an effectively same rate as IV administration. (Can you imagine trying to give your dog a daily shot?) It also shows that much of the glucosamine stays in the body (rebuilding cartilage and easing pain) for a few days after administration, so that three daily doses should about as effective as one daily dose.
The Role of Glucosamine and Chondroitin Sulfates in the Treatment of Degenerative Joint Disease
In treating arthritis, the most effective treatment would provide aid in relieving pain as well as providing some repair for the degradation of the joints involved. Various studies support the use of glucosamine in its ability to both relieve pain and provide some repair for the joint.
Glucosamine – A Controlled Clinical Investigation In Arthritis
A study was conducted to further test the effectiveness of glucosamine treatment in primary or secondary osteoarthritis and the same results were reported. No glucosamine related side effects were encountered.
More Clinical References for Glucosamine and Chondroitin Safety and Side Effects
Be sure to visit the Glucosamine Product Guide for a review of commercially available glucosamine products.